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Can I read A Rationale for Continuing Mass Antibiotic Distributions for Trachoma on EtoBox?
A Rationale for Continuing Mass Antibiotic Distributions for Trachoma by Kathryn J Ray; Travis C Porco; Kevin C Hong; David C Lee; Wondu Alemayehu; Muluken Melese; Takele Lakew; Elizabeth Yi; Jenafir House; Jaya D Chidambaram; John P Whitcher; Bruce D Gaynor; Thomas M Lietman is a Medicine article available to read on EtoBox.
What is A Rationale for Continuing Mass Antibiotic Distributions for Trachoma about?
## Background The World Health Organization recommends periodic mass antibiotic distributions to reduce the ocular strains of chlamydia that cause trachoma, the world's leading cause of infectious blindness. Their stated goal is to control infection, not to completely eliminate it. A single mass distribution can dramatically reduce the prevalence of infection. However, if infection is not eliminated in every individual in the community, it may gradually return back into the community, so often repeated treatments are necessary. Since public health groups are reluctant to distribute antibiotics indefinitely, we are still in need of a proven long-term rationale. Here we use mathematical models to demonstrate that repeated antibiotic distributions can eliminate infection in a reasonable time period. ## Methods We fit parameters of a stochastic epidemiological transmission model to data collected before and 6 months after a mass antibiotic distribution in a region of Ethiopia that is one of the most severely affected areas in the world. We validate the model by comparing our predicted results to Ethiopian data which was collected biannually for two years past the initial mass antibioti
Who reads A Rationale for Continuing Mass Antibiotic Distributions for Trachoma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Kathryn J Ray; Travis C Porco; Kevin C Hong; David C Lee; Wondu Alemayehu; Muluken Melese; Takele Lakew; Elizabeth Yi; Jenafir House; Jaya D Chidambaram; John P Whitcher; Bruce D Gaynor; Thomas M Lietman
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2334)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)