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Can I read Locally advanced breast cancer : Treatment guideline implementation with particular attention to low- and middle-income countries on EtoBox?
Locally advanced breast cancer : Treatment guideline implementation with particular attention to low- and middle-income countries by Nagi S. El Saghir; Alexandru Eniu; Robert W. Carlson; Zeba Aziz; Daniel Vorobiof; Gabriel N. Hortobagyi; on behalf of the Breast Health Global Initiative Systemic Therapy Focus Group is a Medicine article available to read on EtoBox.
What is Locally advanced breast cancer : Treatment guideline implementation with particular attention to low- and middle-income countries about?
The management of locally advanced breast cancer (LABC) is guided by scientific advances but is limited by local resources and expertise. LABC remains very common in low-resource countries. The Systemic Therapy Focus Group met as part of the Breast Health Global Initiative (BHGI) Summit in Budapest, Hungary, in October 2007 to discuss management and implementation of primary systemic therapy (PST) for LABC. PST is standard treatment for large operable breast cancer in enhanced-resource settings and, in all resource settings, should be standard treatment for inoperable breast cancer and for LABC. Standard PST includes anthracycline-based chemotherapy. The addition of sequential taxanes after anthracycline improves pathologic responses and breast-conservation rates and is appropriate at enhanced-resource levels; however, costs and lack of clear survival benefit do not justify their use at limited-resource levels. It remains to define better the role of endocrine therapy as PST, but it is acceptable in elderly women. Aromatase inhibitors have produced better results than tamoxifen in postmenopausal patients and are used in enhanced-resource settings. The less expensive tamoxifen remai
Who reads Locally advanced breast cancer : Treatment guideline implementation with particular attention to low- and middle-income countries?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nagi S. El Saghir; Alexandru Eniu; Robert W. Carlson; Zeba Aziz; Daniel Vorobiof; Gabriel N. Hortobagyi; on behalf of the Breast Health Global Initiative Systemic Therapy Focus Group
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)