Opening book details…
Can I read The environmental risks of pharmaceuticals beyond traditional toxic effects: Chemical differences that can repel or entrap aquatic organisms on EtoBox?
The environmental risks of pharmaceuticals beyond traditional toxic effects: Chemical differences that can repel or entrap aquatic organisms by Jacob, Raquel Sampaio; AraÃojo, Cristiano V.M.; Santos, Lucilaine Valéria de Souza; Moreira, Victor Rezende; Lebron, Yuri Abner Rocha; Lange, Liséte Celina is a Environmental Science article available to read on EtoBox.
What is The environmental risks of pharmaceuticals beyond traditional toxic effects: Chemical differences that can repel or entrap aquatic organisms about?
The aim of the present study was to assess the risks of four different pharmaceutical active compounds (PhACs; diazepam, metformin, omeprazole and simvastatin). Acute and chronic toxicities were studied using the bacterium Aliivibrio fischeri and the microalgae Pseudokirchneriella subcapitata; while the repellency and attractiveness were assessed by avoidance tests with juvenile Cypirinus carpio using a multi-compartmented exposure system. Omeprazole was found to be an acutely toxic drug (EC: 0.015 mg/L), while the other PhACs, except simvastatin, showed some chronic toxicity. Regarding avoidance, simvastatin and omeprazole induced an escape response for 50% of the fish population at 0.032 and 0.144 mg/L, respectively; contrarily, diazepam was attractive, even at lethal concentrations, representing a dangerous trap for organisms. The toxicity of the PhACs seemed not to be directly related to their repellency; and the mode of action seems to determine the repellency or attractiveness of the chemicals. Contamination by PhACs is of concern due to the environmental disturbance they might cause, either due to their acute and chronic toxicity (at the individual level), repellency (at the
Who reads The environmental risks of pharmaceuticals beyond traditional toxic effects: Chemical differences that can repel or entrap aquatic organisms?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- Jacob, Raquel Sampaio; AraÃojo, Cristiano V.M.; Santos, Lucilaine Valéria de Souza; Moreira, Victor Rezende; Lebron, Yuri Abner Rocha; Lange, Liséte Celina
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV; Publons (ISSN 0269-7491)
- Published
- 2020
- Language
- EN
- Field
- Environmental Science (Physical Sciences)