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What is Shiga-like Toxin I Effects in Pigs about?

This study investigates the effects of Shiga-like toxin I (SLT-I) on gnotobiotic pigs, revealing that SLT-I causes significant clinical signs including diarrhea and neurologic symptoms, leading to death or euthanasia within days. Lesions observed include necrosis at the injection site, hemorrhage in the intestines, and severe brain damage, similar to conditions seen in humans and calves affected by enterohemorrhagic E. coli. The findings suggest that SLT-I is responsible for vascular damage and ischemic nec

Author

kulczyk.anya

Language

EN