Opening book details…
Can I read High Correlation of Static First-Minute-Frame (FMF) PET Imaging after ^18^F-Labeled Amyloid Tracer Injection with [^18^F]FDG PET Imaging on EtoBox?
High Correlation of Static First-Minute-Frame (FMF) PET Imaging after ^18^F-Labeled Amyloid Tracer Injection with [^18^F]FDG PET Imaging by Alexander P. Seiffert; Adolfo Gómez-Grande; Alberto Villarejo-Galende; Marta González-Sánchez; Héctor Bueno; Enrique J. Gómez; Patricia Sánchez-González is a Engineering article available to read on EtoBox.
What is High Correlation of Static First-Minute-Frame (FMF) PET Imaging after ^18^F-Labeled Amyloid Tracer Injection with [^18^F]FDG PET Imaging about?
Dynamic early-phase PET images acquired with radiotracers binding to fibrillar amyloid-beta (Aβ) have shown to correlate with [^18^F]fluorodeoxyglucose (FDG) PET images and provide perfusion-like information. Perfusion information of static PET scans acquired during the first minute after radiotracer injection (FMF, first-minute-frame) is compared to [^18^F]FDG PET images. FMFs of 60 patients acquired with [^18^F]florbetapir (FBP), [^18^F]flutemetamol (FMM), and [^18^F]florbetaben (FBB) are compared to [^18^F]FDG PET images. Regional standardized uptake value ratios (SUVR) are directly compared and intrapatient Pearson’s correlation coefficients are calculated to evaluate the correlation of FMFs to their corresponding [^18^F]FDG PET images. Additionally, regional interpatient correlations are calculated. The intensity profiles of mean SUVRs among the study cohort (__r__ = 0.98, __p__ < 0.001) and intrapatient analyses show strong correlations between FMFs and [^18^F]FDG PET images (__r__ = 0.93 ± 0.05). Regional VOI-based analyses also result in high correlation coefficients. The FMF shows similar information to the cerebral metabolic patterns obtained by [^18^F]FDG PET imaging. Th
Who reads High Correlation of Static First-Minute-Frame (FMF) PET Imaging after ^18^F-Labeled Amyloid Tracer Injection with [^18^F]FDG PET Imaging?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- Alexander P. Seiffert; Adolfo Gómez-Grande; Alberto Villarejo-Galende; Marta González-Sánchez; Héctor Bueno; Enrique J. Gómez; Patricia Sánchez-González
- Publisher
- MDPI AG
- Published
- 2021
- Language
- EN
- Field
- Engineering (Physical Sciences)