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Can I read Functional imaging and quantification of multineuronal olfactory responses in C. elegans on EtoBox?
Functional imaging and quantification of multineuronal olfactory responses in C. elegans by Lin, Albert (author);Qin, Shanshan (author);Casademunt, Helena (author);Wu, Min (author);Hung, Wesley (author);Cain, Gregory (author);Tan, Nicolas Z. (author);Valenzuela, Raymond (author);Lesanpezeshki, Leila (author);Venkatachalam, Vivek (author);Pehlevan, Cengiz (author);Zhen, Mei (author);Samuel, Aravinthan D.T. (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Functional imaging and quantification of multineuronal olfactory responses in C. elegans about?
Many animals perceive odorant molecules by collecting information from ensembles of olfactory neurons, where each neuron uses receptors that are tuned to recognize certain odorant molecules with different binding affinity. Olfactory systems are able, in principle, to detect and discriminate diverse odorants using combinatorial coding strategies. We have combined microfluidics and multineuronal imaging to study the ensemble-level olfactory representations at the sensory periphery of the nematode __Caenorhabditis elegans__. The collective activity of __C. elegans__ chemosensory neurons reveals high-dimensional representations of olfactory information across a broad space of odorant molecules. We reveal diverse tuning properties and dose-response curves across chemosensory neurons and across odorants. We describe the unique contribution of each sensory neuron to an ensemble-level code for volatile odorants. We show that a natural stimuli, a set of nematode pheromones, are also encoded by the sensory ensemble. The integrated activity of the __C. elegans__ chemosensory neurons contains sufficient information to robustly encode the intensity and identity of diverse chemical stimuli.
Who reads Functional imaging and quantification of multineuronal olfactory responses in C. elegans?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Lin, Albert (author);Qin, Shanshan (author);Casademunt, Helena (author);Wu, Min (author);Hung, Wesley (author);Cain, Gregory (author);Tan, Nicolas Z. (author);Valenzuela, Raymond (author);Lesanpezeshki, Leila (author);Venkatachalam, Vivek (author);Pehlevan, Cengiz (author);Zhen, Mei (author);Samuel, Aravinthan D.T. (author)
- Publisher
- American Association for the Advancement of Science (AAAS)
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Physical Sciences)