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Can I read Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (celastraceae) on EtoBox?
Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (celastraceae) by Antonio G. González; Benigna M. Tincusi; Isabel L. Bazzocchi; Harukuni Tokuda; Hoyoku Nishino; Takao Konoshima; Ignacio A. Jiménez; Angel G. Ravelo is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (celastraceae) about?
Ten sesquiterpenoids (1-10), with a dihydro-beta-agarofuran skeleton, were isolated from Maytenus cuzcoina (Celastraceae). Their structures were elucidated on the basis of spectral analysis, including homo- and heteronuclear correlations NMR experiments (COSY, ROESY, HMQC and HMBC), and chemical correlations. The compounds have been tested for their inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), as a test for potential cancer chemopreventive agents. Compounds 1-3, 6 and 7 showed strong inhibitory effects on EBV-EA induction (100% inhibition at 1000 mol ratio/TPA). Their structure-activity relationship is discussed.
Who reads Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (celastraceae)?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Antonio G. González; Benigna M. Tincusi; Isabel L. Bazzocchi; Harukuni Tokuda; Hoyoku Nishino; Takao Konoshima; Ignacio A. Jiménez; Angel G. Ravelo
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0968-0896)
- Published
- 2000
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)