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What is Leptin Resistance and Cognitive Decline about?

This review discusses the impact of leptin resistance on hippocampal function and cognitive decline, emphasizing how it disrupts synaptic plasticity and cognitive performance. It highlights the role of high-fat diets in exacerbating leptin resistance and suggests potential therapeutic strategies, including leptin sensitizers and lifestyle interventions. The review aims to identify molecular pathways and therapeutic targets to address cognitive deficits associated with obesity-related leptin resistance.

Author

morbreir

Language

EN