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In asthma, increased FeNO reflects eosinophilicmediated inflammatory pathways moderately well in central and / or peripheral airway sites. In pulmonary hypertension and cystic fibrosis, the role of FeNO monitoring is less clear and therefore less established than in asthma. In COPD, large / central airway maximal NO flux and peripheral / small airway / alveolar NO concentration may be normal.
- Author
- Dallas Beaird
- Language
- EN