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Can I read Pattern of DNA segregation in multipolar anatelophases of different ploidy in euploid and aneuploid mammalian cells cultivated in vitro on EtoBox?
Pattern of DNA segregation in multipolar anatelophases of different ploidy in euploid and aneuploid mammalian cells cultivated in vitro by F. Balitti; M. Rizzoni is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Pattern of DNA segregation in multipolar anatelophases of different ploidy in euploid and aneuploid mammalian cells cultivated in vitro about?
A microdensitometrical analysis of multipolar anatelophases of euploid and aneuploid mammalian cells in vitro has been made in order to study the quantitative distribution of DNA to the poles. In the tripolar anatelophases of aneuploid Chinese hamster cells (obtained using colchicine) DNA is distributed to poles in an almost random way. In the spontaneous tripolar anatelophases of euploid cells of Rhesus, DNA is distributed to the poles in whole number multiples of lc. The following distributions were observed in tetraploid cells: 14 cases of 3:3:2 and 3 cases of 4 : 2 : 2. In triploid cells, 6 cases of 2 : 2 : 2 and 1 case of 3 : 2 : I. Thus we have deduced that each ploidy degree has a preferential distribution of sets and in contrast to the original hypothesis, random segregation of the sets is not the common occurrence. Hypotheses have been made to explain the origin of multipolar mitosis and the preferential distribution of chromatid sets to the poles. The results would confirm the existence of haploid sets of chromatids and would explain the appearance of triploid, pentaploid and hexaploid cells in tissues and cell cultures.
Who reads Pattern of DNA segregation in multipolar anatelophases of different ploidy in euploid and aneuploid mammalian cells cultivated in vitro?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- F. Balitti; M. Rizzoni
- Publisher
- Springer Netherlands; Springer-Verlag; Kluwer Academic Publishers; Springer Science and Business Media LLC (ISSN 0016-6707)
- Published
- 1972
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)