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Cytokine Induction by Respiratory Syncytial Virus and Adenovirus in Bronchial Epithelial Cells by Jong-Seo Yoon; Hyun-Hee Kim; Yoon Lee; Joon-Sung Lee is a Medicine article available to read on EtoBox.

What is Cytokine Induction by Respiratory Syncytial Virus and Adenovirus in Bronchial Epithelial Cells about?

## Abstract In order to broaden our knowledge of the primary immune responses to respiratory syncytial virus (RSV) and adenovirus infections, we compared the concentrations of interleukin (IL)‐6, IL‐8, and regulated on activation, normal T cell expressed and secreted (RANTES) produced in vitro during RSV and adenovirus infections of bronchial epithelial cells. We infected BEAS‐2B cells—a human bronchial epithelial cell line—with RSV, adenovirus serotype 3, or serotype 7 and measured the concentrations of IL‐6, IL‐8, and RANTES in the cell culture supernatants. When the multiplicity of infection (MOI) was 1, RSV induced the production of markedly higher concentrations of IL‐6, IL‐8, and RANTES than the adenovirus. When the MOI of the adenovirus was increased to 100, the production of IL‐6 and IL‐8 increased. However, the amounts produced were still lower than those produced by RSV with the MOI of 1. There was no statistically significant increase in the production of RANTES in spite of the MOI of the adenovirus was increased to 100. Adenovirus serotype 7 induced the production of considerably more IL‐6 and IL‐8 than serotype 3 in the MOI of 100. However, neither adenovirus serotype

Who reads Cytokine Induction by Respiratory Syncytial Virus and Adenovirus in Bronchial Epithelial Cells?

Author

Jong-Seo Yoon; Hyun-Hee Kim; Yoon Lee; Joon-Sung Lee

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-6863)

Published

2007

Language

EN

Field

Medicine (Health Sciences)