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This research paper discusses the development of a novel nanogel delivery system for the anticancer drug 5-Fluorouridine (5-FU) using poly-α, β-polyasparthydrazide (PAHy) and 3,3′-dithiodipropionic acid (DTDPA) to enhance redox-responsive drug release. The PAHy-based nanogels demonstrated significant glutathione sensitivity and anti-tumor efficacy, making them promising candidates for targeted drug delivery. Characterization techniques confirmed the nanogels

Author

Iraj mesgarzadeh

Language

EN