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What is Notch and FGF Signaling in Development about?

Notch signaling regulates cell development and differentiation through receptor cleavage and transcriptional regulation in the nucleus. While traditionally viewed as a linear pathway, recent studies show it interacts with many other pathways. Notch also regulates somitogenesis together with fibroblast growth factor (FGF) through an oscillating clock and receding gradient model that controls segment formation. There are multiple FGFs and receptors that play roles in endocrine and paracrine signaling through

Author

AxelBlom

Language

EN