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Low-cost Microfluidic Testbed for Molecular Communications with Integrated Hydrodynamic Gating and Screen-printed Sensors by Albay, Maide Miray; Akyol, Eren; Mirlou, Fariborz; Beker, Levent; Kuscu, Murat is a scholarly article available to read on EtoBox.

What is Low-cost Microfluidic Testbed for Molecular Communications with Integrated Hydrodynamic Gating and Screen-printed Sensors about?

Molecular Communications (MC), transferring information via chemical signals, holds promise for transformative healthcare applications within the Internet of Bio-Nano Things (IoBNT) framework. Despite promising advances toward practical MC systems, progress has been constrained by experimental testbeds that are costly, difficult to customize, and require labor-intensive fabrication. Here, we address these challenges by introducing a low-cost ($\sim$\$1 per unit), rapidly fabricated ($<$1 hour), and highly customizable microfluidic testbed that integrates hydrodynamic gating and screen-printed potentiometric sensors. This platform enables precise spatiotemporal control over chemical signals and supports reconfigurable channel architectures along with on-demand sensor functionalization. As a proof of concept, we demonstrate a pH-based MC system combining a polyaniline (PANI)-functionalized sensor for real-time signal detection with a programmable hydrodynamic gating architecture, patterned in a double-sided adhesive tape, as the transmitter. By dynamically mixing phosphate-buffered saline (PBS) with an acidic solution (pH 3), the testbed reliably generates pH-encoded pulses. Experime

Author

Albay, Maide Miray; Akyol, Eren; Mirlou, Fariborz; Beker, Levent; Kuscu, Murat

Published

2025

Language

EN