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Can I read The Cutoff of Ferritin for Evaluation of Hypothyroidism in Patients With Thalassemia on EtoBox?
The Cutoff of Ferritin for Evaluation of Hypothyroidism in Patients With Thalassemia by Adel Baghersalimi; Afagh H. Rad; Shahin Koohmanaee; Bahram Darbandi; Morteza M. Mirzaee; Vahid Aminzadeh; Abdolreza Medghalchi; Setila Dalili is a Medicine article available to read on EtoBox.
What is The Cutoff of Ferritin for Evaluation of Hypothyroidism in Patients With Thalassemia about?
## Background: Thalassemia major is a genetic disease with a recessive autosomal pattern of inheritance that occurs as a result of disorder in hemoglobin synthesis. Researchers aimed to investigate the cutoff of ferritin for the development of hypothyroidism in patients with thalassemia major. ## Materials and Methods: This was a retrospective analytic cross-sectional study that was conducted on the medical records of patients with thalassemia major. Overt hypothyroidism was defined as thyroid stimulating hormone (TSH) level of >6.5 mIU/L and T4 level of 6.5 mIU/L and T4 level of >4.2 ng/dL. Data were gathered by a form including age, sex, weight, height, body mass index, thyroid test results, and the mean of last 3 consecutive hemoglobin and ferritin levels. ## Results: In this study, 67 patients were evaluated. The mean age of the participants was 15.37±3.73 years. The frequency of subclinical hypothyroidism was 10.4%, and no cases of clinical hypothyroidism were noted as well as secondary hypothyroidism. Although there was a significant linear correlation between mean ferritin level and TSH (__P__=0.008), no significant correlation was noted between levels of ferritin and T4 le
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- Author
- Adel Baghersalimi; Afagh H. Rad; Shahin Koohmanaee; Bahram Darbandi; Morteza M. Mirzaee; Vahid Aminzadeh; Abdolreza Medghalchi; Setila Dalili
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)