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What is Citrullination about?
The commentary discusses the significance of citrullination and anti-citrullinated protein antibodies (ACPAs) in the pathophysiology and diagnosis of rheumatoid arthritis (RA). It highlights the development of the CCP2 test, which is now a gold standard for RA diagnosis, and the role of citrullination in tissue destruction and inflammation associated with RA. Additionally, the document outlines the relationship between genetic and environmental factors, such as smoking, in the onset and progression of ACPA-
- Author
- Utsav Prajapati
- Language
- EN