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What is Enhancing Iloperidone Solubility via Complexation about?
The study investigates the enhancement of solubility and bioavailability of the antipsychotic drug Iloperidone (ILO) through the formation of binary and ternary complexes with Hydroxypropyl b-cyclodextrin (HPbCD) and auxiliary agents such as Tartaric acid (TA) and Kolliphor P-188 (KP). Results indicated significant improvements in solubility and complexation efficiency, particularly with TA, as confirmed by various characterization techniques including PXRD, DSC, FT-IR, and NMR. The findings suggest that th
- Author
- Vishwajeet Ghorpade
- Language
- EN