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Lipid Droplets Big and Small:Basic Mechanisms ThatMake Them All by Robin W. Klemm1and Pedro Carvalho2 is a book available to read on EtoBox.
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KeywordsThe Annual Review of Cell and Developmental Biologylipid droplet, LD, LD biogenesis, LD protein targeting, LD contact sites,is online at cellbio.annualreviews.orgLD heterogeneity, LD size control, adipocyte © 2024 by the author(s). This work isLipid droplets (LDs) are dynamic storage organelles with central roles inlicensed under a Creative Commons Attribution 4.0lipid and energy metabolism. They consist of a core of neutral lipids, suchInternational License, which permits unrestrictedas triacylglycerol, which is surrounded by a monolayer of phospholipids anduse, distribution, and reproduction in any medium,provided the original author and source are credited.specialized surface proteins. The surface composition determines many ofSee credit lines of images or other third-partythe LD properties, such as size, subcellular distribution, and interactionmaterial in this article for license information.with partner organelles. Considering the diverse energetic and metabolicdemands of various cell types, it is not surprising that LDs are highly heterogeneous within and between cell types. Despite their diversity, all LDsshare a common biogenesis mechanism. However, adipocytes hav
- Author
- Robin W. Klemm1and Pedro Carvalho2
- Published
- 2024
- Language
- EN
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