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Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox by Nobuyo Higashi; Katsuyuki Imai; Mitsuru Sato; Takeya Sato; Naosuke Kojima; Mitsutaka Miura; Heidi L Wold; Jan Øivind Moskaug; Trond Berg; Kaare R Norum; Norbert Roos; Kenjiro Wake; Rune Blomhoff; Haruki Senoo is a Medicine article available to read on EtoBox.

What is Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox about?

We examined the liver of adult polar bears, arctic foxes, and rats by gold chloride staining, fluorescence microscopy for the detection of autofluorescence of vitamin A, hematoxylin-eosin staining, staining with Masson's trichrome, Ishii and Ishii's silver impregnation, and transmission electron microscopical morphometry. The liver lobules of the arctic animals showed a zonal gradient in the storage of vitamin A. The density (i.e., cell number per area) of hepatic stellate cells was essentially the same among the zones. These results indicate that the hepatic stellate cells of the polar bears and arctic foxes possess heterogeneity of vitamin A-storing capacity in their liver lobules.

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Author

Nobuyo Higashi; Katsuyuki Imai; Mitsuru Sato; Takeya Sato; Naosuke Kojima; Mitsutaka Miura; Heidi L Wold; Jan Øivind Moskaug; Trond Berg; Kaare R Norum; Norbert Roos; Kenjiro Wake; Rune Blomhoff; Haruki Senoo

Publisher

BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, c2002-2012.; Springer Science and Business Media LLC (ISSN 1476-5926)

Published

2004

Language

EN

Field

Medicine (Health Sciences)