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Can I read Dual role of microRNA-1297 in the suppression and progression of human malignancies on EtoBox?
Dual role of microRNA-1297 in the suppression and progression of human malignancies by Shahin Alizadeh-Fanalou; Mohsen Khosravi; Fatemeh Alian; Shirin Rokhsartalb-Azar; Ali Nazarizadeh; Maryam Karimi-Dehkordi; Forogh Mohammadi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Dual role of microRNA-1297 in the suppression and progression of human malignancies about?
MicroRNAs (miRNAs) are endogenous, non-coding, single-stranded and tiny RNAs that modulate several biological functions, more importantly, the pathophysiology of numerous human cancers. They are bound with target mRNAs and thereby regulate gene expression at post-transcriptional levels. MiRNAs can either trigger cancer progression as an oncogene or alleviate it as a tumor suppressor. Abnormal expression of microRNA-1297 (miR-1297) has been noticed in several human cancers suggesting a distinct role for the miRNA in tumorigenesis. More specifically, it is both up-regulated and down-regulated in various cancers suggesting that it can act as both tumor suppressor and oncogene. This review systematically highlights the different roles of miR-1297 in the pathophysiology of human cancers, explains the mechanisms underlying miR-1297-mediated tumorigenesis, and discusses its potential prognostic, diagnostic, and therapeutic importance.
Who reads Dual role of microRNA-1297 in the suppression and progression of human malignancies?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Shahin Alizadeh-Fanalou; Mohsen Khosravi; Fatemeh Alian; Shirin Rokhsartalb-Azar; Ali Nazarizadeh; Maryam Karimi-Dehkordi; Forogh Mohammadi
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)