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Development of Daily Rhythmicity in Heart Rate and Locomotor Activity in the Human Fetus by Paliko I Kintraia; Medea G Zarnadze; Nicolas P Kintraia; Ia G Kashakashvili is a Neuroscience article available to read on EtoBox.

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## Background Very little is known about the perinatal genesis of circadian rhythmicity in the human fetus. Some researchers have found evidence of rhythmicity early on in fetal development, whereas others have observed a slow development of rhythmicity during several years after birth. ## Method Rhythms of fetal heartbeat and locomotor activity were studied in women with physiological course of pregnancy at 16 to 40 gestational weeks. Observations were conducted continuously for 24 h using the method of external electrocardiography, which provided simultaneous detection of the changes in maternal and fetal heartbeat as well as assessment of daily locomotor activity of the fetus. During the night-time, electroencephalogram, myogram, oculogram and respiration of the mother were registered in parallel with fetal external electrocardiography. ## Results Although we found no significant daily rhythmicity in heart rate per se in the human fetus, we developed a new method for the assessment of 24-h fetal cardiotachogram that allowed us to identify daily rhythmicity in the short-term pattern of heart beating. We found that daily rhythmicity of fetal electrocardiogram resembles that of the

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Author

Paliko I Kintraia; Medea G Zarnadze; Nicolas P Kintraia; Ia G Kashakashvili

Publisher

BioMed Central; Ubiquity Press, Ltd.; [London]: BioMed Central, c2003-2014; [London]: Ubiquity Press (ISSN 1740-3391)

Published

2005

Language

EN

Field

Neuroscience (Life Sciences)