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Cyclotides are stable globular microproteins characterized by a unique head-to-tail cyclized backbone and a cystine knot structure, making them promising candidates for peptide-based diagnostics and therapeutics. They exhibit remarkable stability against degradation and can modulate intracellular protein interactions, with applications in various biological activities. The article reviews their discovery, structural features, and potential biotechnological applications, highlighting their significance in mo

Author

Văn Hiếu Phan

Language

EN