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This document discusses the M and N blood group system. It notes that the M and N antigens are found on the glycoprotein glycophorin A and differ in their amino acid composition at positions 1 and 5. Anti-M and Anti-N are naturally occurring antibodies that are recovered from rabbit serum. While Anti-M is commonly an IgG antibody, Anti-N is typically an IgM antibody. Both antibodies are cold reactive and do not bind complement or react with enzyme treated red blood cells.

Author

Nathalia Villanueva

Language

EN