About this Medicine article

Bone Outcomes Following Sleeve Gastrectomy in Adolescents and Young Adults with Obesity Versus Non-surgical Controls by Misra, Madhusmita; Singhal, Vibha; Carmine, Brian; Bose, Amita; Kelsey, Megan M.; Stanford, Fatima Cody; Bram, Jennifer; Aidlen, Jeremy; Inge, Thomas; Bouxsein, Mary L.; Bredella, Miriam A. is a Medicine article available to read on EtoBox.

## Background: Sleeve gastrectomy is the most commonly performed weight loss surgery in adolescents with moderate-to-severe obesity. while studies in adults have reported on the deleterious effects of gastric bypass surgery on bone structure and strength estimates, data are lacking for the impact of sleeve gastrectomy on these measures in adolescents. ## Objective: To evaluate the impact of sleeve gastrectomy on bone outcomes in adolescents and young adults over 12 months using dual energy x-ray absorptiometry (dxa) and high resolution peripheral quantitative computed tomography (hrpqct). ## Participants and methods: We enrolled 44 youth 14-22 years old with moderate to severe obesity; 22 underwent sleeve gastrectomy and 22 were followed without surgery (16 females and 6 males in each group). at baseline and 12 months, dxa was used to assess areal bone mineral density (abmd), hrpqct of the distal radius and tibia was performed to assess bone geometry, microarchitecture and volumetric bmd (vbmd), and finite element analysis to assess strength estimates (stiffness and failure load). these analyses were adjusted for age, sex, race and the bone measure at baseline. fasting blood sample

Author

Misra, Madhusmita; Singhal, Vibha; Carmine, Brian; Bose, Amita; Kelsey, Megan M.; Stanford, Fatima Cody; Bram, Jennifer; Aidlen, Jeremy; Inge, Thomas; Bouxsein, Mary L.; Bredella, Miriam A.

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 8756-3282)

Published

2020

Language

EN

Field

Medicine (Health Sciences)