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A comprehensive guide to cutting-edge tools in ADME research The last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible rang This book comprehensively covers the state-of-the-art and cutting-edge technologies in an integrated fashion for applications in ADME studies of small molecular drugs. Each chapter provides descriptions of the technologies, application scope and limitations, optimal conditions for intended results, protocols, case studies, and future developments. Edited By Donglu Zhang, Sekhar Surapaneni. Includes Bibliographical References And Index.

Author

Donglu Zhang, Sekhar Surapaneni

Publisher

John Wiley & Sons, Incorporated

Published

2012

Language

EN

ISBN

9780470542781

Subjects

Science, Technology, Chemistry