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Gene Expression Analysis in Cartilage by In Situ Hybridization by Sabatini, Massimo; Pastoureau, Philippe; De Ceuninck, Frdric is a scholarly article available to read on EtoBox.

What is Gene Expression Analysis in Cartilage by In Situ Hybridization about?

Osteoarthritis, the most common form of arthritis, imposes a significant burden of suffering on a growing population of the elderly. Even today, its poorly understood pathophysiology limits the discovery of molecular targets for pharmacological intervention and there are few effective medical treatments beyond pain control and surgery. In Cartilage and Osteoarthritis a distinguished panel of researchers, physicians, and opinion leaders in this challenging field describe their updated classical, but still evolving, techniques, as well as many emerging methods that promise to add significantly to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. The protocols follow the successful Methods in Molecular MedicineTM series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and ti

Author

Sabatini, Massimo; Pastoureau, Philippe; De Ceuninck, Frdric

Publisher

Humana Press

Published

2004

Language

EN

ISBN

9781588292476