Can I read Mutagenic Impurities in Pharmaceuticals on EtoBox?

Mutagenic Impurities in Pharmaceuticals by Vijay Naganaboina is a document available to read on EtoBox.

What is Mutagenic Impurities in Pharmaceuticals about?

The document discusses the analysis of potentially mutagenic impurities in pharmaceuticals, highlighting that many structural classes of these impurities have lower carcinogenic potencies than those used to derive the default Threshold of Toxicological Concern (TTC). It suggests that acceptable daily intakes (ADIs) for certain structural classes can be higher than the default TTC, based on data from 108 synthetic routes across 13 companies. The findings support the use of more tailored calculations for acce

Author

Vijay Naganaboina

Language

EN