About this document
1,3-Azoles: Structure and Reactivity by Simona Scutarasu is a document available to read on EtoBox.
1) Imidazole, oxazole, and thiazole are five-membered ring systems containing three carbons, one nitrogen, and an additional heteroatom. They have been known since the 19th century. 2) Oxazole was first prepared in 1947, about 100 years after the first substituted oxazole. Thiazoles were first synthesized in the 1870s. 3) These heterocycles are present in many natural products and secondary metabolites such as thiamine, penicillin, histidine, and epothilone A. Their reactivity includes participation in
- Author
- Simona Scutarasu
- Language
- EN