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Can I read Mitochondria Regulate the Amplitude of Simple and Complex Calcium Oscillations on EtoBox?
Mitochondria Regulate the Amplitude of Simple and Complex Calcium Oscillations by Vladimir Grubelnik; Ann Zahle Larsen; Ursula Kummer; Lars Folke Olsen; Marko Marhl is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Mitochondria Regulate the Amplitude of Simple and Complex Calcium Oscillations about?
## w Ž . x In a mathematical model for simple calcium oscillations Biophys. Chem. 71 1998 125 , it has been shown that mitochondria play an important role in the maintenance of constant amplitudes of cytosolic Ca 2q oscillations. Simple plausible rate laws for Ca 2q fluxes across the inner mitochondrial membrane have been used in this model. Here we show that it is possible to use the same rate laws as a plug-in element in other existing mathematical models and obtain the same effect on amplitude regulation. This result appears to be universal, independent of the type of model 2q 2q w and the type of Ca oscillations. We demonstrate this on two models for spiking Ca oscillations J. Biol. Chem. Ž . Ž . x 2q 266 1991 11068; Cell Calcium 14 1993 311 and on two recent models for bursting Ca oscillations; one of them w Ž . x being a receptor-operated model Biophys. J. 79 2000 1188 and the other one being a store-operated model w Ž . x BioSystems 57 2000 75 .
Who reads Mitochondria Regulate the Amplitude of Simple and Complex Calcium Oscillations?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Vladimir Grubelnik; Ann Zahle Larsen; Ursula Kummer; Lars Folke Olsen; Marko Marhl
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0301-4622)
- Published
- 2001
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)