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Imipenem is a carbapenem antibiotic that inhibits bacterial cell-wall synthesis and is co-administered with cilastatin to reduce renal metabolism. It has a broad spectrum of activity against various Gram-positive and Gram-negative bacteria but should not be used if a narrower spectrum antibiotic is available. Caution is advised in patients with renal impairment and CNS disorders due to potential side effects such as seizures and phlebitis.

Author

lidya.tjan

Language

EN