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The study investigates the effects of the antipsychotic drug aripiprazole on rat liver cells, revealing that it induces persistent mitochondrial hyperpolarisation and moderate oxidative stress, which may lead to drug-induced liver injury. Aripiprazole treatment results in increased reactive oxygen species production and a shift towards glycolysis for ATP production, while also affecting the activity of antioxidant enzymes. The findings suggest that aripiprazole may enhance resilience to oxidative stress, ma
- Author
- Vivaan
- Language
- EN