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Can I read Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis on EtoBox?
Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis by Minghua Zheng; Jianling Bai; Bosi Yuan; Feng Lin; Jie You; Mingqin Lu; Yuewen Gong; Yongping Chen is a Medicine article available to read on EtoBox.
What is Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis about?
## Background Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography and benefit of pharmacological treatment is unclear. Although prophylactic use of corticosteroid for reduction of pancreatic injury after ERCP has been evaluated, discrepancy about beneficial effect of corticosteroid on pancreatic injury still exists. The aim of current study is to evaluate effectiveness and safety of corticosteroid in prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). ## Methods We employed the method recommended by the Cochrane Collaboration to perform a meta-analysis of seven randomized controlled trials (RCTs) of corticosteroid in prevention of post-ERCP pancreatitis (PEP) around the world. ## Results Most of the seven RCTs were of high quality. When the RCTs were analyzed, odds ratios (OR) for corticosteroid were 1.13 [95% CI (0.89~1.44), p = 0.32] for PEP, 1.61 [95% CI (0.74~3.52), p = 0.23] for severe PEP, 0.92 [95% CI (0.57~1.48), p = 0.73] for post-ERCP hyperamylasemia respectively. The results indicated that there were no beneficial effects of corticosteroid on acute pancreatitis and hyperamylasemia. No evidence o
Who reads Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Minghua Zheng; Jianling Bai; Bosi Yuan; Feng Lin; Jie You; Mingqin Lu; Yuewen Gong; Yongping Chen
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-230X)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)