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Mature teratoma identified after postchemotherapy surgery in patients with disseminated nonseminomatous testicular germ cell tumors : A plea for an aggressive surgical approach by Dirk J. A. Sonneveld; Dirk Th. Sleijfer; Heimen Schraffordt Koops; Mariel E. Keemers-Gels; Willemina M. Molenaar; Harald J. Hoekstra is a Medicine article available to read on EtoBox.

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## Background: Mature teratoma is often found in resected retroperitoneal residual tumor masses (rrtm) after chemotherapy for disseminated nonseminomatous testicular germ cell tumors (nstgct). the aim of this report is to describe the clinical course of patients after resection of residual teratoma, with particular emphasis on relapse with either growing mature teratoma or secondary non-germ cell malignancy. ## Methods: During the period 1979-1995, 113 patients underwent a laparotomy for resection of rrtm after chemotherapy for nstgct. only patients with mature teratoma in the rrtm were included in the current study, and data on the patients who experienced relapse were studied in detail. ## Results: Mature teratoma was found in 51 patients (45.1%) with rrtm resected after chemotherapy. nine of these 51 patients (17.6%) relapsed; the relapses resulted from growing mature teratoma in 5 patients (9.8%), secondary non-germ cell malignancy in 3 patients (5.9%), and recurrent germ cell malignancy in 1 patient (2.0%). the primary treatment for all relapsing patients was surgical excision. all five patients with growing mature teratoma are alive without evidence of disease, as is the pati

Who reads Mature teratoma identified after postchemotherapy surgery in patients with disseminated nonseminomatous testicular germ cell tumors : A plea for an aggressive surgical approach?

Author

Dirk J. A. Sonneveld; Dirk Th. Sleijfer; Heimen Schraffordt Koops; Mariel E. Keemers-Gels; Willemina M. Molenaar; Harald J. Hoekstra

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1998

Language

EN

Field

Medicine (Health Sciences)