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Improvement in Delivery of Ischemic Stroke Treatments but Stagnation of Clinical Outcomes in Young Adults in South Korea by Jonguk Kim; Jun Yup Kim; Jihoon Kang; Beom Joon Kim; Moon-Ku Han; Jeong-Yoon Lee; Tai Hwan Park; Ji Sung Lee; Keon-Joo Lee; Joon-Tae Kim; Kang-Ho Choi; Jong-Moo Park; Kyusik Kang; Soo Joo Lee; Jae Guk Kim; Jae-Kwan Cha; Dae-Hyun Kim; Kyung Bok Lee; Jun Lee; Keun-Sik Hong; Yong-Jin Cho; Hong-Kyun Park; Byung-Chul Lee; Kyung-Ho Yu; Mi-Sun Oh; Dong-Eog Kim; Wi-Sun Ryu; Jay Chol Choi; Jee-Hyun Kwon; Wook-Joo Kim; Dong-Ick Shin; Kyu Sun Yum; Sung Il Sohn; Jeong-ho Hong; Sang-Hwa Lee; Juneyoung Lee; Philip B. Gorelick; Hee-Joon Bae is a scholarly article available to read on EtoBox.

What is Improvement in Delivery of Ischemic Stroke Treatments but Stagnation of Clinical Outcomes in Young Adults in South Korea about?

Background There is limited information on the delivery of acute stroke therapies and secondary preventive measures and clinical outcomes over time in young adults with acute ischemic stroke (AIS). This study investigated whether advances in these treatments improved outcomes in this population.MethodsUsing a prospective multicenter stroke registry in Korea, young adults (aged 1850 years) with AIS hospitalized between 2008 and 2019 were identified. The observation period was divided into four epochs: 20082010, 20112013, 20142016, and 20172019. Secular trends for patient characteristics, treatments, and outcomes were analyzed.Results A total of 7,050 eligible patients (mean age 43.1; men 71.9%) were registered. The mean age decreased from 43.6 to 42.9 years (Ptrend=0.01). Current smoking decreased, whereas obesity increased. Other risk factors remained unchanged. Intravenous thrombolysis and mechanical thrombectomy rates increased over time from 20082010 to 20172019 (9.5% to 13.8% and 3.2% to 9.2%, respectively; Ptrends<0.01). Door-to-needle time improved (Ptrend<0.001), but onset-to-door and door-to-puncture time remained constant. Secondary prevention including dual antiplatelets

Author

Jonguk Kim; Jun Yup Kim; Jihoon Kang; Beom Joon Kim; Moon-Ku Han; Jeong-Yoon Lee; Tai Hwan Park; Ji Sung Lee; Keon-Joo Lee; Joon-Tae Kim; Kang-Ho Choi; Jong-Moo Park; Kyusik Kang; Soo Joo Lee; Jae Guk Kim; Jae-Kwan Cha; Dae-Hyun Kim; Kyung Bok Lee; Jun Lee; Keun-Sik Hong; Yong-Jin Cho; Hong-Kyun Park; Byung-Chul Lee; Kyung-Ho Yu; Mi-Sun Oh; Dong-Eog Kim; Wi-Sun Ryu; Jay Chol Choi; Jee-Hyun Kwon; Wook-Joo Kim; Dong-Ick Shin; Kyu Sun Yum; Sung Il Sohn; Jeong-ho Hong; Sang-Hwa Lee; Juneyoung Lee; Philip B. Gorelick; Hee-Joon Bae

Publisher

Cold Spring Harbor Laboratory

Published

2023

Language

EN