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The study focuses on synthesizing a generation four PAMAM dendrimer to encapsulate tetramethylscutellarein (TMScu) to enhance its solubility and potential bioactivity. The dendrimer demonstrated a high encapsulation efficiency of 77.8% and increased TMScu solubility at varying pH levels, with stable formulations observed under controlled conditions. The findings suggest that PAMAM dendrimers can effectively improve the delivery and efficacy of poorly soluble flavonoids in biomedical applications.

Author

manu.ciateq

Language

EN