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The study investigates the effects of gentamicin on ototoxicity and nephrotoxicity in female Sprague-Dawley rats, highlighting that the severity of these effects varies based on the circadian timing of treatment. Results indicate that ototoxicity and nephrotoxicity occur through separate mechanisms, with greater toxicity observed in rats treated at the beginning of their activity span compared to those treated at the beginning of their rest span. The findings suggest that the timing of gentamicin administra

Author

dawraty111

Language

EN