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Typical and atypical carcinoids within the pulmonary APUD tumor spectrum by DeCaro, Louis F.; Paladugu, Rao; Benfield, John R.; Lovisatti, Leonardo; Pak, Hyun; Teplitz, Raymond L. is a Medicine article available to read on EtoBox.

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## Typical and atypical carcinoids within the pulmonary APUD tumor spectrum The behavior of pulmonary APUD tumors is not constant; management is controversial, and morphology has reached its limit as a tool for prognostic assessment and therapeutic planning. We have studied 24 patients with carcinoids; 17 patients with typical carcinoids presented with Stage I disease, but one patient later died most probably of small cell undifferentiated lung cancer (SCLC). Seven patients with atypical carcinoids included three with Stage III cancers, one patient with simultaneous bilateral carcinoids, and one patient with simultaneous adenocarcinoma. Of 17 patients with typical carcinoids, 16 or 92% are disease free or died of unrelated causes. Of seven patients with atypical carcinoids,five or?I % are disease free. Tumor doubling time of atypical carcinoids, was 79.6 months (45 to 120) or six times shorter than that of typical carcinoids (p < 0.05). Two of the three deaths from cancer were probably from SCLC and one from a synchronous adenocarcinoma. Review of diagnostic material from 12 patients with SCLC who survived a mean of 41 months (24 to 134) showed that diagnosis had rested on cytology

Who reads Typical and atypical carcinoids within the pulmonary APUD tumor spectrum?

Author

DeCaro, Louis F.; Paladugu, Rao; Benfield, John R.; Lovisatti, Leonardo; Pak, Hyun; Teplitz, Raymond L.

Publisher

CTSNet; American Association for Thoracic Surgery; Mosby Inc.; Elsevier BV; Publons (ISSN 1097-685X)

Published

1983

Language

EN

Field

Medicine (Health Sciences)