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About this Biochemistry, Genetics and Molecular Biology article

Synthesis of Bioprocesses Using Physical Properties Data by M. A. Steffens; E. S. Fraga; I. D. L. Bogle is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

The aim of this article is to illustrate and evaluate a synthesis procedure which has been extended to tackle bioprocesses. Physical property information is used to screen candidate units thereby reducing the size of the synthesis problem. In this way, only units which exploit large property differences between components in a stream are selected. This is important for bioprocesses because of the large number of components and wide range of unit operations which are available. The screening technique and bioprocess-unit-design methodologies have been incorporated within an implicit enumeration algorithm which was developed for chemical process synthesis and is implemented in Java programming language. An important advantage is the ability of the bioprocess synthesis software to generate a ranked list of flowsheets which may subsequently be analyzed in more detail. Two case studies are used to evaluate the bioprocesssynthesis technique. The first system involves a product which is secreted from the host organism. The second has significantly different characteristics in that the product is intracellular and forms inclusion bodies. The latter case study, in particular, is a large syn

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
M. A. Steffens; E. S. Fraga; I. D. L. Bogle
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); Wiley - V C H Verlag GmbbH & Co.; Wiley (ISSN 0006-3592)
Published
2000
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)