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The study investigates the role of long noncoding RNA NEAT1 in promoting ferroptosis in tumors through the miR-362-3p/MIOX axis. NEAT1 expression is increased by ferroptosis inducers, leading to enhanced ROS production and ferroptosis in cancer cells. The findings suggest that targeting NEAT1 may offer a therapeutic strategy for hepatocellular carcinoma patients with high NEAT1 expression.

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xuzhaoyuan1102

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EN