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MR1 Ligandome: T Cell Detection Insights by seq is a document available to read on EtoBox.
What is MR1 Ligandome: T Cell Detection Insights about?
MR1 is a nonconventional MHC molecule that presents microbial metabolites to T cells. A study used mass spectrometry to identify a broad array of ligands from Escherichia coli and Mycobacterium smegmatis that are presented by MR1. These MR1-presented ligands from diverse microbes can be distinguished by different T cell receptors and can have inhibitory or activating effects on T cells. The findings broaden the understanding of MR1
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- EN