Can I read Journal of Neurochemistry - 2020 - Socodato - Dopamine D1 Receptor Signaling and Endocannabinoid Cooperate To Fuel Striatal on EtoBox?

Journal of Neurochemistry - 2020 - Socodato - Dopamine D1 Receptor Signaling and Endocannabinoid Cooperate To Fuel Striatal by isabellyrm97 is a document available to read on EtoBox.

What is Journal of Neurochemistry - 2020 - Socodato - Dopamine D1 Receptor Signaling and Endocannabinoid Cooperate To Fuel Striatal about?

This editorial highlights the interplay between dopamine D1 receptor signaling and endocannabinoids in regulating striatal plasticity, particularly focusing on the role of 2-arachidonoyl glycerol (2-AG) in synaptic modulation. The study by Shonesy et al. demonstrates that activation of D1 receptors and subsequent phosphorylation of diacylglycerol lipase (DGL) alpha by PKA enhances 2-AG synthesis, which is crucial for short-term synaptic plasticity in the corticostriatal circuit. This research opens avenues

Author

isabellyrm97

Language

EN