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Can I read Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts. on EtoBox?

Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts. by D E Brash; W A Franklin; G B Sancar; A Sancar; W A Haseltine is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts. about?

The effect of purified Escherichia coli DNA photolyase on the UV light-induced pyrimidine-pyrimidone (6-4) photoproduct and cyclobutane pyrimidine dimer was investigated in vitro using enzyme purified from cells carrying the cloned phr gene (map position, 15.7 min). Photoproducts were examined both as site-specific lesions in end-labeled DNA and as chromatographically identified products in uniformly labeled DNA. E. coli DNA photolyase removed cyclobutane dimers but had no activity on pyrimidine-pyrimidone (6-4) photoproducts. Photoreactivation can therefore be used to separate the biological effects of these two UV light-induced molecular lesions.

Who reads Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts.?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
D E Brash; W A Franklin; G B Sancar; A Sancar; W A Haseltine
Publisher
Elsevier BV
Published
1985
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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