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Acne vulgaris is a multifactorial disorder primarily affecting adolescents, characterized by comedones, papules, pustules, and nodules, with significant psychological and economic impacts. It affects approximately 40-50 million individuals in the US annually, with a peak incidence in young people aged 12-24, and can persist into adulthood. The pathogenesis involves factors like follicular hyperkeratinization, hormonal influences, inflammation, and the presence of Cutibacterium acnes, with genetic and dietar

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1499gizem

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EN