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Influence of Developmental and Hormonal Factors on Bone Health in Adolescent Females: a Cross-sectional Study and Review of the Literature by Aikaterini Sarra; Maria Karantza; Maria Papaefthymiou; Helen Soultanakis; Athanasios Papaefstathiou; Polixeni Nikolaidou; Chryssa Bakoula; George Chrousos is a Medicine article available to read on EtoBox.
What is Influence of Developmental and Hormonal Factors on Bone Health in Adolescent Females: a Cross-sectional Study and Review of the Literature about?
Objective: To study bone density in healthy Greek girls going through puberty and determine the influence of developmental and hormonal factors. Design: Sixty healthy female adolescents (average age of 13.88 ± 2.53 years) were included. Bone mineral density (BMD) was measured at the hip by DXA (dual energy X-ray absorptiometry). Pubertal stage was determined by Tanner ' s criteria. Creatinine, calcium, phosphorus, parathyroid hormone, calcitonin and 25-OH-vitamin D levels were measured in blood samples. The European physical fitness test battery (EUROFIT) was used to assess the parameters of physical fitness that are related to strength. Results: Adolescent girls had a mean ( ± SD) BMD value of 0.947 ± 0.144 g/cm 2 at the total hip (total hip BMD). Tanner ' s stage for pubic hair and body mass index (BMI) constituted significant, positive and independent predicting factors for bone density of total hip. Deficiency of 25OH-vitamin D was a negative predicting factor of bone density. Blood levels of calcium and phosphorus, the hours that adolescents devoted to sports, and handgrip strength, were independent predicting factors of bone density at the hip. Conclusions: Bone density and c
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- Author
- Aikaterini Sarra; Maria Karantza; Maria Papaefthymiou; Helen Soultanakis; Athanasios Papaefstathiou; Polixeni Nikolaidou; Chryssa Bakoula; George Chrousos
- Publisher
- Walter de Gruyter GmbH
- Published
- 2013
- Language
- EN
- Field
- Medicine (Health Sciences)