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Can I read A Smart Methodology to Fabricate Electrospun Chitosan Nanofiber Matrices for Regenerative Engineering Applications on EtoBox?
A Smart Methodology to Fabricate Electrospun Chitosan Nanofiber Matrices for Regenerative Engineering Applications by Ahmed A. Nada; Roshan James; Namdev B. Shelke; Matthew D. Harmon; Hassan M. Awad; Rajaram K. Nagarale; Sangamesh G. Kumbar is a Materials Science article available to read on EtoBox.
What is A Smart Methodology to Fabricate Electrospun Chitosan Nanofiber Matrices for Regenerative Engineering Applications about?
The electrospinning of chitosan remains challenging due to its rigid crystalline structure, insufficient viscosity, and limited solubility in common organic solvents. This work presents a “smart” chitosan modification that allows electrospinning irrespective of molecular weight or deacetylation value and without blending with synthetic polymers. A novel derivative, namely 2‐nitrobenzyl‐chitosan (NB), at various molar compositions of chitosan:2‐nitrobenzaldehyde (1:1 (NB‐1), 1:0.5 (NB‐2), 1:0.25 (NB‐3)) was synthesized by the reaction between amino groups of chitosan and aldehyde groups of 2‐nitrobenzaldehyde. In this Schiff base, 2‐nitrobenzaldehyde protects the amine functionalities of chitosan and improves its solubility in trifluoroacetic acid. 2‐nitrobenzaldehyde is a photoactivatable‐caged compound that cleaves off from iminochitosan on ultraviolet exposure yielding neat chitosan. Derivatives showed improved solubility in trifluoroacetic acid and dynamic viscosities in the range of 1.34 ± 0.7 to 12 ± 0.5 Pa·s based on the degree of substitution and concentration. Electrospinning conditions were optimized to produce bead free nanofibers in the range of 100–600 nm, and concentra
Who reads A Smart Methodology to Fabricate Electrospun Chitosan Nanofiber Matrices for Regenerative Engineering Applications?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Ahmed A. Nada; Roshan James; Namdev B. Shelke; Matthew D. Harmon; Hassan M. Awad; Rajaram K. Nagarale; Sangamesh G. Kumbar
- Publisher
- Wiley
- Published
- 2014
- Language
- EN
- Field
- Materials Science (Physical Sciences)