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What is Global vs Local Sequence Alignment about?

This document discusses sequence alignment and its basis in evolution. It defines key terms like sequence identity, similarity, and homology. It explains that global alignment compares full sequences while local alignment finds most similar regions. Dot matrix and dynamic programming methods are described for performing alignments, with dynamic programming constructing a scoring matrix to determine optimal matches between sequences. Gap penalties are introduced to account for insertions and deletions in evo

Author

Anny morales Aguirre

Language

EN