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Combination Cryotherapy and Intralesional Corticosteroid Versus Steroid Monotherapy in the Treatment of Keloids by Alexa J. Cohen; Sahithi Talasila; Bojan Lazarevic; Lauren Banner; Laura Gleason; Kabir Malkani; Jouni Uitto; Neda Nikbakht is a Medicine article available to read on EtoBox.

What is Combination Cryotherapy and Intralesional Corticosteroid Versus Steroid Monotherapy in the Treatment of Keloids about?

## Abstract ## Background Keloids are common and have significant negative effects on quality of life. There is a need for more effective treatment approaches for keloids. ## Aims We investigated treatment outcomes of intralesional triamcinolone acetonide (IL TAC) compared with combination IL TAC and cryotherapy, including changes in pruritus, pain, and keloid size. ## Patients/Methods We performed a prospective study of patients referred to one provider who treated patients with combination therapy and compared them to a historic control cohort treated with IL TAC alone. All patients were seen at Thomas Jefferson University between 2019 and 2021. Patient demographics, location of keloids, and inciting events were recorded. Pruritus and pain scores were self‐reported by patients using a 10‐point Likert scale administered as standard of care. Changes in keloid size were denoted as “No change,” “up to 50% decrease,” “more than 50% decrease,” and “completely flattened.” ## Results While both treatments produced a significant reduction in mean pruritus and pain scores, there was no difference between the two treatment groups (p = 0.3933 and p = 0.2123, respectively). A greater percenta

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Author

Alexa J. Cohen; Sahithi Talasila; Bojan Lazarevic; Lauren Banner; Laura Gleason; Kabir Malkani; Jouni Uitto; Neda Nikbakht

Publisher

Wiley

Published

2022

Language

EN

Field

Medicine (Health Sciences)