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Can I read Preliminary Trial of Nonrecombinant Interferon Alpha in Recurrent Squamous Cell Carcinoma of the Head and Neck on EtoBox?
Preliminary Trial of Nonrecombinant Interferon Alpha in Recurrent Squamous Cell Carcinoma of the Head and Neck by Dr. Daniel R. Vlock; Dr. Jonas Johnson; Dr. Eugene Myers; Mr. Roger Day; Mr. William E. Gooding; Dr. Theresa Whiteside; Ms. Karen Pelch; Ms. Barbara Sigler; Dr. Robin Wagner; Ms. Denise Colao; Ms. Deborah Rust is a Medicine article available to read on EtoBox.
What is Preliminary Trial of Nonrecombinant Interferon Alpha in Recurrent Squamous Cell Carcinoma of the Head and Neck about?
Fourteen patients with recurrent squamous cell carcinoma of the head and neck (SCCHN) were treated with 10 x 10' U of nonrecombinant interferon alpha (IFN) intramuscularly (IM) daily for 3 days every 28 days. There were 11 men and 3 women, with ages ranging from 48 to 74 years. Patients had previously been treated with surgery (9 patients), radiotherapy (13 patients), or chemotherapy (8 patients). All patient: had measurable disease by physical exam and radiologic evaluation and a performance status of 5 2 (ECOG). Patients were treated for a minimum of 3 months and continued on therapy until disease progression. The dose and treatment schedule of IFN was well-tolerated. Toxicities included low-grade fever, mild anorexia, and malaise. Treatment was stopped in 1 patient due to the development of atrial fibrillation. One death occurred as a complication of aspiration pneumonia 2 weeks following the onset of therapy and was not felt to be related to IFN therapy. O f the 14 patients treated, there was 1 complete response (30+ months) of a base of tongue pri-From the Divisions of Medical Oncology (Dr. Vlock and Ms. Pelch. Colao,
Who reads Preliminary Trial of Nonrecombinant Interferon Alpha in Recurrent Squamous Cell Carcinoma of the Head and Neck?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Dr. Daniel R. Vlock; Dr. Jonas Johnson; Dr. Eugene Myers; Mr. Roger Day; Mr. William E. Gooding; Dr. Theresa Whiteside; Ms. Karen Pelch; Ms. Barbara Sigler; Dr. Robin Wagner; Ms. Denise Colao; Ms. Deborah Rust
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1043-3074)
- Published
- 1990
- Language
- EN
- Field
- Medicine (Health Sciences)