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Exercise in Type 1 (insulin-dependent) diabetic patients treated with continuous subcutaneous insulin infusion: Prevention of exercise induced hypoglycaemia by G. E. Sonnenberg; F. W. Kemmer; M. Berger is a Medicine article available to read on EtoBox.

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The study was performed to investigate the effects of mild to moderate exercise on blood glucose levels, metabolite concentrations and responses of counterregulatory hormones in tightly controlled Type 1 (insulin-dependent) diabetic patients treated by continuous subcutaneous insulin infusion, and to quantify the measures necessary to prevent acute and late exercise-induced hypoglycaemia. Seven male patients started a 60 min exercise period 90 min after an insulin bolus and a standard breakfast; they were monitored during a post-exercise resting period of 5 h 30 min. Different basal and premeal insulin infusion rates were applied. (Near)normoglycaemia prevailed throughout the study during the control protocol when the subjects did not exercise and received their usual insulin dose. When they exercised without changing the insulin dose, four patients were forced to stop due to hypoglycaemia. This effect of exercise could be attenuated but not completely avoided if the basal infusion rate of insulin was discontinued during the exercise period. The pronounced increase in catecholamine and growth hormone concentrations during exercise were not sufficient to prevent hypoglycaemic reacti

Who reads Exercise in Type 1 (insulin-dependent) diabetic patients treated with continuous subcutaneous insulin infusion: Prevention of exercise induced hypoglycaemia?

Author

G. E. Sonnenberg; F. W. Kemmer; M. Berger

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0012-186X)

Published

1990

Language

EN

Field

Medicine (Health Sciences)