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Sacubitril/valsartan is indicated for reducing cardiovascular death and hospitalization in patients with chronic heart failure and reduced ejection fraction. The recommended starting dose is 49 mg/51 mg twice daily, with a target maintenance dose of 97 mg/103 mg, while adjustments are necessary for patients with renal or hepatic impairments. The drug has several warnings, including risks during pregnancy and potential adverse effects such as hypotension and angioedema.

Author

ashifistiak1995

Language

EN